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http://infotec.repositorioinstitucional.mx/jspui/handle/1027/521| High affinity promoter binding of STOP1 is essential for early expression of novel aluminum-induced resistance genes GDH1 and GDH2 in Arabidopsis | |
| JAVIER MORA MACIAS DAGOBERTO ARMENTA MEDINA | |
| Acceso Abierto | |
| Atribución-NoComercial-CompartirIgual | |
| https://academic.oup.com/jxb/article/72/7/2769/6106577 | |
| Acid soils--Tropics Arabidopsis thaliana | |
| Malate efflux from roots, which is regulated by the transcription factor STOP1 (SENSITIVE-TO-PROTON-RHIZOTOXICITY1) and mediates aluminum-induced expression of ALUMINUM-ACTIVATED-MALATE-TRANSPORTER1 (AtALMT1), is critical for aluminum resistance in Arabidopsis thaliana. Several studies showed that AtALMT1 expression in roots is rapidly observed in response to aluminum; this early induction is an important mechanism to immediately protect roots from aluminum toxicity. Identifying the molecular mechanisms that underlie rapid aluminum resistance responses should lead to a better understanding of plant aluminum sensing and signal transduction mechanisms. In this study, we observed that GFP-tagged STOP1 proteins accumulated in the nucleus soon after aluminum treatment. The rapid aluminum-induced STOP1-nuclear localization and AtALMT1 induction were detected in the presence of a protein synthesis inhibitor, suggesting that post-translational regulation is involved in these events. STOP1 also regulated rapid aluminum-induced expression for other genes that carry a functional/high-affinity STOP1-binding site in their promoter, including STOP2, GLUTAMATE-DEHYDROGENASE1 and 2 (GDH1 and 2). However STOP1 did not regulate Al resistance genes which have no functional STOP1-binding site such as ALUMINUM-SENSITIVE3, suggesting that the binding of STOP1 in the promoter is essential for early induction. Finally, we report that GDH1 and 2 which are targets of STOP1, are novel aluminum-resistance genes in Arabidopsis. | |
| Journal of Experimental Botany INFOTEC Centro de Investigación e Innovación en Tecnologías de la Información y Comunicación | |
| 22-01-2021 | |
| Artículo | |
| Mutsutomo Tokizawa, Dagoberto Armenta Medina, Javier Mora-Macías. (2021). La unión del promotor de alta afinidad de STOP1 es esencial para la expresión temprana de los nuevos genes de resistencia inducida por alumi | |
| Inglés | |
| Normas APA 7.ª edición | |
| GENÉTICA MOLECULAR DE PLANTAS | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Aparece en las colecciones: | Artículos |
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